SOCRATE PRESENTATION

siric-visuel-accueilThe SOCRATE program

The SOCRATE program covers three areas of research involving the integration of basic with translational and clinical research as well as social sciences on the same site. Every work-packages are co-directed by a clinician researcher and a fundamental researcher : the SOCRATE project aims at breaking barriers between clinical and basic research. This innovative structuration has the ambition to boost the emergence of new treatments for cancer patients in an unprecedented time scale.

 

Le programme scientifique :

siric-vignette-adn   fleche-vert-droite-9x9 Program 1
DNA Damage Response (DDR)

Scientif coordinator(s):

Patricia Kannouche & Sophie Postel-Vinay


Aims:

To ensure the integrity of the genome and hence the fitness and viability of cells, DNA lesions that are formed as a result of various toxic assaults are normally repaired by an elaborate network of DNA damage response (DDR) pathways...Learn more
     
siric-vignette-immuno  

fleche-vert-droite-9x9Program 2
Immuno-Oncology

Scientif coordinator(s):

Laurence Zitvogel & Aurélien Marabelle

 

Aims :


The discovery of cancer immune checkpoints and the successes of immune- and tumor -targeted antibodies have changed the landscape of the clinical management of various malignancies...Learn more

     
siric-vignette-mm  

fleche-vert-droite-9x9 Program 3

Cancer Molecular Dynamics

 

Co-Headed by Pr Fabrice André and Dr Olivier Bernard
Aims:

 

Molecular medicine also called precision or personalized medicine is a scientific approach based on molecular analyses that drive methods for early diagnosis, and guidance for targeted therapies...Learn more

SIRIC IN FRANCE




Five certified SIRIC province

  Establishment Acronym Direction
  Lyon  LYRIC  Pr J-Y. Blay
  Nante  ILIAD  Pr P. Moreau
 

Bordeaux

 BRIO

 Pr P. Soubeyran

  Montpellier  SIRIC Pr M. Ychou

 

Three labeled SIRIC in Ile-France

  Establishment Acronym Direction
  Institut Curie    Pr O. Delattre
  HEGP et Cochin  CARPEM  Pr P. Laurent-Puig
  La salle Pêtrière CURAMUS  Pr J-P. SPANO
  Gustave Roussy  SOCRATE
 Pr E. Deutsch

IntegraGen et Gustave Roussy

Mise en place d’une unité de séquençage clinique à très haut-débit. Cette plate-forme de séquençage sera exploitée par IntegraGen au sein de Gustave Roussy et permettra d’identifier les variations génétiques somatiques sur l’ensemble de l’exome tumoral des patients et d’orienter leur prise en charge.

C. Robert : 3 New England Journal of Medicine, 2 Nature et 1 Lancet !

Grosse production scientifique de la part de l’équipe de Caroline Robert (équipe Mélanome U981) avec la publication de 6 papiers à très haut impact entre Septembre et Novembre 2014.